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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase Src' and Ligand = 'BDBM334331'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM334331
PNG
(1-(4-((2-((3-Ethynyl-5-methoxyphenyl)amino)pyrimid...)
Show SMILES COc1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(nn4-c4ccc(C)cc4)C(C)C)c4ccccc34)n2)cc(c1)C#C
Show InChI InChI=1S/C37H33N7O3/c1-6-25-19-26(21-28(20-25)46-5)39-36-38-18-17-35(42-36)47-33-16-15-31(29-9-7-8-10-30(29)33)40-37(45)41-34-22-32(23(2)3)43-44(34)27-13-11-24(4)12-14-27/h1,7-23H,2-5H3,(H,38,39,42)(H2,40,41,45)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.60E+3n/an/an/an/an/an/a



RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED

US Patent


Assay Description
c-Src and Syk Enzyme InhibitionThe inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a...


US Patent US9732063 (2017)

More data for this
Ligand-Target Pair