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Found 4 Enz. Inhib. hit(s) with Target = 'Purine nucleoside phosphorylase' and Ligand = 'BDBM50280445'
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50280445((E)-2-{2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl...)
Affinity DataKi:  0.800nMAssay Description:Inhibitory activity against calf spleen purine nucleoside phosphorylase in the presence of 1 mM (pi) orthophosphonateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280445((E)-2-{2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl...)
Affinity DataKi:  1.80nMAssay Description:Inhibitory activity against human erythrocytic purine nucleoside phosphorylase in the presence of 1 mM (pi) orthophosphonateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50280445((E)-2-{2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl...)
Affinity DataIC50:  60nMAssay Description:Inhibitory concentration against calf spleen purine nucleoside phosphorylase in the presence of 50 mM (pi) orthophosphonateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280445((E)-2-{2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl...)
Affinity DataIC50:  77nMAssay Description:Inhibitory concentration against human erythrocytic purine nucleoside phosphorylase in the presence of 50 mM (pi) orthophosphonateMore data for this Ligand-Target Pair
In DepthDetails Article