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Found 3 Enz. Inhib. hit(s) with Target = 'RAC-alpha serine/threonine-protein kinase' and Ligand = 'BDBM256872'
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM256872(US10654855, Example 68 | US11236095, Example 68 | ...)
Affinity DataIC50:  12nMpH: 7.5 T: 2°CAssay Description:This assay detects inhibitors of AKT1 (PKBα) kinase activity using Caliper LabChip LC3000. The Caliper off-chip incubation mobility shift assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM256872(US10654855, Example 68 | US11236095, Example 68 | ...)
Affinity DataIC50:  12nMAssay Description:Following addition of compound or control to the assay plate, 6p1 peptide mix containing 3 μM substrate (5-FAM-GRPRTSSFAEG-CONH2; CRB) and 40 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM256872(US10654855, Example 68 | US11236095, Example 68 | ...)
Affinity DataIC50:  12nMAssay Description:For Echo dosing the solvent was 100% DMSO. A master plate was prepared with 40 ul of 10 mM stock from our Primary Liquid Store in quadrant 1 of a Lab...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent