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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'RAF proto-oncogene serine/threonine-protein kinase (RAF-1)' and Ligand = 'BDBM316962'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
RAF proto-oncogene serine/threonine-protein kinase (RAF-1)


(Homo sapiens (Human))
BDBM316962
PNG
(N-{2,4-Difluoro-3-[4- (tetrahydro-pyran-4- ylamino...)
Show SMILES Fc1ccc(NS(=O)(=O)c2ccc(cc2)C(F)(F)F)c(F)c1C(=O)c1c[nH]c2ncnc(NC3CCOCC3)c12
Show InChI InChI=1S/C25H20F5N5O4S/c26-17-5-6-18(35-40(37,38)15-3-1-13(2-4-15)25(28,29)30)21(27)20(17)22(36)16-11-31-23-19(16)24(33-12-32-23)34-14-7-9-39-10-8-14/h1-6,11-12,14,35H,7-10H2,(H2,31,32,33,34)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Plexxikon Inc.

US Patent


Assay Description
Assays for biochemical and cell based activity are known in the art, for example, as described in PCT publication WO 2007/002433, the disclosure of w...


US Patent US9617267 (2017)

More data for this
Ligand-Target Pair