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Found 5 Enz. Inhib. hit(s) with Target = 'Retinoid isomerohydrolase' and Ligand = 'BDBM323415'
TargetRetinoid isomerohydrolase(Homo sapiens (Human))
Acucela

US Patent
LigandPNGBDBM323415(3-Amino-1-(3-(cyclohexylmethoxy)Phenyl)Propan-1-Ol...)
Affinity DataIC50: <100nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
TargetRetinoid isomerohydrolase(Bos taurus (Bovine))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM323415(3-Amino-1-(3-(cyclohexylmethoxy)Phenyl)Propan-1-Ol...)
Affinity DataIC50:  172nMAssay Description:Inhibition of RPE65 in bovine retinal pigment epithelium microsomes assessed as decrease of 11-cis-retinol using trans-retinol measured after 1 hr by...More data for this Ligand-Target Pair
TargetRetinoid isomerohydrolase(Bos taurus (Bovine))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM323415(3-Amino-1-(3-(cyclohexylmethoxy)Phenyl)Propan-1-Ol...)
Affinity DataIC50:  190nMAssay Description:Inhibition of RPE65 in bovine retinal pigment epithelium microsomes assessed as decrease of 11-cis-retinol using trans-retinol measured after 1 hr by...More data for this Ligand-Target Pair
TargetRetinoid isomerohydrolase(Bos taurus (Bovine))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM323415(3-Amino-1-(3-(cyclohexylmethoxy)Phenyl)Propan-1-Ol...)
Affinity DataIC50: <1.00E+3nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
TargetRetinoid isomerohydrolase(Bos taurus (Bovine))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM323415(3-Amino-1-(3-(cyclohexylmethoxy)Phenyl)Propan-1-Ol...)
Affinity DataEC50:  172nMAssay Description:Inhibition of RPE65 in bovine RPE microsomes assessed as reduction in 11-cis-retinol production using all-trans-retinol as substrate pre-incubated wi...More data for this Ligand-Target Pair