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Found 2 Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 1' and Ligand = 'BDBM299194'
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kadmon

US Patent
LigandPNGBDBM299194((KL-00254) N-(1H-Indazol-5-yl)-2-(5-methoxyisoindo...)
Affinity DataIC50:  3.50E+3nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kadmon

US Patent
LigandPNGBDBM299194((KL-00254) N-(1H-Indazol-5-yl)-2-(5-methoxyisoindo...)
Affinity DataIC50: >1.00E+4nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent