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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Ribosomal protein S6 kinase alpha 2' and Ligand = 'BDBM184188'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (Human))
BDBM184188
PNG
(US9150577, 41)
Show SMILES O=C(Nc1nc2cc(ccc2[nH]1)C#N)c1ccc2cc3C(=O)NCCCn3c2c1
Show InChI InChI=1S/C21H16N6O2/c22-11-12-2-5-15-16(8-12)25-21(24-15)26-19(28)14-4-3-13-9-18-20(29)23-6-1-7-27(18)17(13)10-14/h2-5,8-10H,1,6-7H2,(H,23,29)(H2,24,25,26,28)
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KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 4.90n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair