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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Ribosomal protein S6 kinase alpha 2' and Ligand = 'BDBM184192'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (Human))
BDBM184192
PNG
(US9150577, 45)
Show SMILES CCCS(=O)(=O)c1ccc2[nH]c(NC(=O)c3ccc4cc5C(=O)NCCCn5c4c3)nc2c1
Show InChI InChI=1S/C23H25N5O4S/c1-2-10-33(31,32)16-6-7-17-18(13-16)26-23(25-17)27-21(29)15-5-4-14-11-20-22(30)24-8-3-9-28(20)19(14)12-15/h4-7,11-13,33H,2-3,8-10H2,1H3,(H,24,30)(H,31,32)(H2,25,26,27,29)
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Similars

US Patent
n/an/a 3.60n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair