BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Ribosomal protein S6 kinase alpha 2' and Ligand = 'BDBM184195'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (Human))
BDBM184195
PNG
(US9150577, 48)
Show SMILES CC1CCNC(=O)c2cc3ccc(cc3n12)C(=O)Nc1nc2cc(Cl)ccc2[nH]1
Show InChI InChI=1S/C21H18ClN5O2/c1-11-6-7-23-20(29)18-8-12-2-3-13(9-17(12)27(11)18)19(28)26-21-24-15-5-4-14(22)10-16(15)25-21/h2-5,8-11H,6-7H2,1H3,(H,23,29)(H2,24,25,26,28)
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 2.5n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair