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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Ribosomal protein S6 kinase alpha 2' and Ligand = 'BDBM184198'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (Human))
BDBM184198
PNG
(US9150577, 51)
Show SMILES Fc1ccc2[nH]c(NC(=O)c3ccc4cc5C(=O)NCCCn5c4c3)nc2c1
Show InChI InChI=1S/C20H16FN5O2/c21-13-4-5-14-15(10-13)24-20(23-14)25-18(27)12-3-2-11-8-17-19(28)22-6-1-7-26(17)16(11)9-12/h2-5,8-10H,1,6-7H2,(H,22,28)(H2,23,24,25,27)
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UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 5.20n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair