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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Ribosomal protein S6 kinase alpha 2' and Ligand = 'BDBM184251'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (Human))
BDBM184251
PNG
(US9150577, 120)
Show SMILES CN(C)c1cccc(Cn2cc(NC(=O)c3ccc4cc5C(=O)NCCCn5c4c3)cn2)c1
Show InChI InChI=1S/C25H26N6O2/c1-29(2)21-6-3-5-17(11-21)15-30-16-20(14-27-30)28-24(32)19-8-7-18-12-23-25(33)26-9-4-10-31(23)22(18)13-19/h3,5-8,11-14,16H,4,9-10,15H2,1-2H3,(H,26,33)(H,28,32)
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PC cid
PC sid
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Similars

US Patent
n/an/a 3.80n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair