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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Ribosomal protein S6 kinase alpha 2' and Ligand = 'BDBM50360296'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (Human))
BDBM50360296
PNG
(CHEMBL1933283 | US9150577, 96)
Show SMILES CN(C)CCCn1c(NC(=O)c2ccc3cc4C(=O)NCCCn4c3c2)nc2ccccc12
Show InChI InChI=1S/C25H28N6O2/c1-29(2)12-6-14-31-20-8-4-3-7-19(20)27-25(31)28-23(32)18-10-9-17-15-22-24(33)26-11-5-13-30(22)21(17)16-18/h3-4,7-10,15-16H,5-6,11-14H2,1-2H3,(H,26,33)(H,27,28,32)
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Similars

US Patent
n/an/a 21n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair