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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'SUMO-activating enzyme subunit 2 (SAE2)' and Ligand = 'BDBM329880'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
SUMO-activating enzyme subunit 2 (SAE2)


(Homo sapiens (Human))
BDBM329880
PNG
((rac)-((1R,2R,3S,4R)-4-(2-(6-chlorobenzo[b]thiophe...)
Show SMILES NS(=O)(=O)OC[C@H]1C[C@@H](Nc2ccnc3cc(nn23)-c2cc3ccc(Cl)cc3s2)[C@H](O)[C@@H]1O
Show InChI InChI=1S/C20H20ClN5O5S2/c21-12-2-1-10-6-16(32-15(10)7-12)13-8-18-23-4-3-17(26(18)25-13)24-14-5-11(19(27)20(14)28)9-31-33(22,29)30/h1-4,6-8,11,14,19-20,24,27-28H,5,9H2,(H2,22,29,30)/t11-,14-,19-,20+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
Article
US Patent
n/an/a 55n/an/an/an/an/an/a



Millennium Pharmaceuticals, Inc.

US Patent


Assay Description
he UAE enzymatic reaction totals 50 μL and contains 50 mmol HEPES (pH 7.5), 0.05% BSA, 2.5 mM MgCl2, 0.1 uM ATP, 8 nM GST-Ubc-2, 35 nM flag-ubiq...


US Patent US9796725 (2017)


Article DOI: 10.1021/jm0701019
BindingDB Entry DOI: 10.7270/Q23T9KC6
More data for this
Ligand-Target Pair