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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase AKT' and Ligand = 'BDBM126572'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase AKT


(Homo sapiens (human))
BDBM126572
PNG
(US8772283, 16)
Show SMILES COc1cccc2OCn3c(nc(c3-c3ccccc3)-c3ccc(cc3)C3(N)CC(O)(C3)C3CC3)-c12
Show InChI InChI=1S/C30H29N3O3/c1-35-23-8-5-9-24-25(23)28-32-26(27(33(28)18-36-24)20-6-3-2-4-7-20)19-10-12-21(13-11-19)29(31)16-30(34,17-29)22-14-15-22/h2-13,22,34H,14-18,31H2,1H3
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MMDB

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Similars

AffyNet 
US Patent
n/an/a 0.350n/an/an/an/an/an/a



Taiho Pharmaceutical Co., Ltd.

US Patent


Assay Description
Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...


US Patent US8772283 (2014)

More data for this
Ligand-Target Pair