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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase AKT2' and Ligand = 'BDBM312541'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase AKT2


(Homo sapiens (human))
BDBM312541
PNG
(US9604989, Example 28)
Show SMILES COCCOc1cc(nn2c(c(nc12)-c1ccc(cc1)C1(N)CCC1)-c1ccccc1)C(N)=O
Show InChI InChI=1S/C26H27N5O3/c1-33-14-15-34-21-16-20(24(27)32)30-31-23(18-6-3-2-4-7-18)22(29-25(21)31)17-8-10-19(11-9-17)26(28)12-5-13-26/h2-4,6-11,16H,5,12-15,28H2,1H3,(H2,27,32)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.40n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH; BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
His-tagged human recombinant kinase full-length Akt2 expressed in insect cells and activated by PDK1 was purchased form Invitrogen (part number PV 39...


US Patent US9604989 (2017)

More data for this
Ligand-Target Pair