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Found 2 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase B-raf' and Ligand = 'BDBM50146587'
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Semmelweis University

Curated by ChEMBL
LigandPNGBDBM50146587(CHEMBL3764571)
Affinity DataIC50: >1.25E+4nMAssay Description:Inhibition of B-Raf V600E mutant (unknown origin) using MEK1 K97M as substrate preincubated for 90 mins followed by substrate addition measured after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Semmelweis University

Curated by ChEMBL
LigandPNGBDBM50146587(CHEMBL3764571)
Affinity DataIC50: >1.25E+4nMAssay Description:Inhibition of wild-type B-Raf (unknown origin) using MEK1 K97M as substrate preincubated for 90 mins followed by substrate addition measured after 1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed