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Found 4 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase Chk1' and Ligand = 'BDBM14605'
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM14605(1-(4-amino-5-chloro-2-methoxyphenyl)-3-(5-cyanopyr...)
Affinity DataKi:  4nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM14605(1-(4-amino-5-chloro-2-methoxyphenyl)-3-(5-cyanopyr...)
Affinity DataIC50:  4nMAssay Description:Abbott Kinase Enzymatics_CHK1/289 CDC25c - IC50(uM) (IC50)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM14605(1-(4-amino-5-chloro-2-methoxyphenyl)-3-(5-cyanopyr...)
Affinity DataIC50:  5nMAssay Description:ChemBL affinity - Published Abbott papersMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM14605(1-(4-amino-5-chloro-2-methoxyphenyl)-3-(5-cyanopyr...)
Affinity DataIC50:  5nMpH: 7.4 T: 2°CAssay Description:Chk1 kinase activity was assayed in reaction buffer containing substrate, enzyme, and inhibitor in the presence of 5uM ATP/[gamma-33P] ATP. 33P incor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed