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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase PIM' and Ligand = 'BDBM352077'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase PIM


(Homo sapiens (Human))
BDBM352077
PNG
((3R,4R,5S)-3-Amino-1-(3-(((6-(2,6-difluoro-3-(1-hy...)
Show SMILES C[C@H]1CN(C[C@@H](N)[C@@H]1O)c1ccncc1NCc1ccc(F)c(n1)-c1c(F)ccc(c1F)C1(O)CC1
Show InChI InChI=1S/C26H28F3N5O2/c1-14-12-34(13-19(30)25(14)35)21-6-9-31-11-20(21)32-10-15-2-4-18(28)24(33-15)22-17(27)5-3-16(23(22)29)26(36)7-8-26/h2-6,9,11,14,19,25,32,35-36H,7-8,10,12-13,30H2,1H3/t14-,19+,25+/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
Article
US Patent
n/an/a<10n/an/an/an/an/an/a



Incyte Corporation

US Patent


Assay Description
Pim-1 and Pim-3 kinase assays-20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...


US Patent US9802918 (2017)


Article DOI: 10.1021/jm031057+
BindingDB Entry DOI: 10.7270/Q2F47R9T
More data for this
Ligand-Target Pair