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Found 2 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase PLK1' and Ligand = 'BDBM50297985'
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297985((R)-3-(1-(4-((tert-butylamino)methyl)-2-(difluorom...)
Affinity DataIC50:  9.80nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297985((R)-3-(1-(4-((tert-butylamino)methyl)-2-(difluorom...)
Affinity DataEC50:  1.90E+4nMAssay Description:Inhibition of PLK1-mediated mitosis in human HeLaS3 cells after 18 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed