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Found 5 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-1' and Ligand = 'BDBM50364777'
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Zarqa University

Curated by ChEMBL
LigandPNGBDBM50364777(CHEMBL1952142)
Affinity DataIC50:  1nMAssay Description:Inhibition of human recombinant PIM1 in presence of ATP by ELISA based spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Zarqa University

Curated by ChEMBL
LigandPNGBDBM50364777(CHEMBL1952142)
Affinity DataIC50:  1nMAssay Description:Inhibition of His tagged human recombinant PIM1 using PIM tide (ARKRRRHPSGPPTA) as substrate incubated for 1 hr by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Zarqa University

Curated by ChEMBL
LigandPNGBDBM50364777(CHEMBL1952142)
Affinity DataIC50:  1nMAssay Description:Inhibition of PIM1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Zarqa University

Curated by ChEMBL
LigandPNGBDBM50364777(CHEMBL1952142)
Affinity DataEC50:  70nMAssay Description:Inhibition of PIM1 in human NCI-H1299 cells assessed as reduction in BAD phosphorylation at Ser-112 residue incubated for 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Zarqa University

Curated by ChEMBL
LigandPNGBDBM50364777(CHEMBL1952142)
Affinity DataEC50:  70nMAssay Description:Inhibition of human PIM1 expressed in H1299 cells assessed as inhibition of BAD phosphorylation at S112 in absense of serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed