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Found 2 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-2' and Ligand = 'BDBM119389'
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM119389(US8669361, 116 | US9573943, Example 116)
Affinity DataKi:  26.2nM ΔG°:  -43.3kJ/molepH: 7.2 T: 2°CAssay Description:PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J. F., a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM119389(US8669361, 116 | US9573943, Example 116)
Affinity DataKi:  26.2nMpH: 7.2Assay Description:PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J. F., a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent