BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-2' and Ligand = 'BDBM352100'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase pim-2


(Homo sapiens (Human))
BDBM352100
PNG
(4-[(3S,5R)-3-Amino-5-methylpiperidin-1-yl]-N-{[6-(...)
Show SMILES C[C@@H]1C[C@H](N)CN(C1)c1ccncc1NCc1cccc(n1)-c1c(F)cccc1F
Show InChI InChI=1/C23H25F2N5/c1-15-10-16(26)14-30(13-15)22-8-9-27-12-21(22)28-11-17-4-2-7-20(29-17)23-18(24)5-3-6-19(23)25/h2-9,12,15-16,28H,10-11,13-14,26H2,1H3/t15-,16+/s2
PDB
MMDB

KEGG

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
Article
US Patent
n/an/a 550n/an/an/an/an/an/a



Incyte Corporation

US Patent


Assay Description
Pim-1 and Pim-3 kinase assays-20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...


US Patent US9802918 (2017)


Article DOI: 10.1021/jm031057+
BindingDB Entry DOI: 10.7270/Q2F47R9T
More data for this
Ligand-Target Pair