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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-2' and Ligand = 'BDBM352136'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase pim-2


(Homo sapiens (Human))
BDBM352136
PNG
(4-((3S,5R)-3-Amino-5-(trifluoromethyl)piperidin-1-...)
Show SMILES N[C@H]1C[C@H](CN(C1)c1ccncc1NCc1ccc(F)c(n1)-c1c(F)cc(cc1F)C1CCOCC1)C(F)(F)F
Show InChI InChI=1/C28H29F6N5O/c29-21-2-1-20(38-27(21)26-22(30)9-17(10-23(26)31)16-4-7-40-8-5-16)12-37-24-13-36-6-3-25(24)39-14-18(28(32,33)34)11-19(35)15-39/h1-3,6,9-10,13,16,18-19,37H,4-5,7-8,11-12,14-15,35H2/t18-,19+/s2
PDB
MMDB

KEGG

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
Article
US Patent
n/an/a<100n/an/an/an/an/an/a



Incyte Corporation

US Patent


Assay Description
Pim-1 and Pim-3 kinase assays-20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...


US Patent US9802918 (2017)


Article DOI: 10.1021/jm031057+
BindingDB Entry DOI: 10.7270/Q2F47R9T
More data for this
Ligand-Target Pair