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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-2' and Ligand = 'BDBM352142'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase pim-2


(Homo sapiens (Human))
BDBM352142
PNG
(4-[(3S,5R)-3-Amino-5-methylpiperidin-1-yl]-N-({6-[...)
Show SMILES C[C@@H]1C[C@H](N)CN(C1)c1ccncc1NCc1ccc(F)c(n1)-c1c(F)cc(cc1F)N1CCCC(F)C1
Show InChI InChI=1/C28H32F4N6/c1-17-9-19(33)16-38(14-17)26-6-7-34-13-25(26)35-12-20-4-5-22(30)28(36-20)27-23(31)10-21(11-24(27)32)37-8-2-3-18(29)15-37/h4-7,10-11,13,17-19,35H,2-3,8-9,12,14-16,33H2,1H3/t17-,18?,19+/s2
PDB
MMDB

KEGG

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
Article
US Patent
n/an/a<100n/an/an/an/an/an/a



Incyte Corporation

US Patent


Assay Description
Pim-1 and Pim-3 kinase assays-20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...


US Patent US9802918 (2017)


Article DOI: 10.1021/jm031057+
BindingDB Entry DOI: 10.7270/Q2F47R9T
More data for this
Ligand-Target Pair