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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-3' and Ligand = 'BDBM352131'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase pim-3


(Homo sapiens (Human))
BDBM352131
PNG
(4-[(3S,5R)-3-Amino-5-methylpiperidin-1-yl]-N-({6-[...)
Show SMILES COC1(CCOCC1)c1cc(F)c(c(F)c1)-c1nc(CNc2cnccc2N2C[C@H](C)C[C@H](N)C2)ccc1F
Show InChI InChI=1/C29H34F3N5O2/c1-18-11-20(33)17-37(16-18)26-5-8-34-15-25(26)35-14-21-3-4-22(30)28(36-21)27-23(31)12-19(13-24(27)32)29(38-2)6-9-39-10-7-29/h3-5,8,12-13,15,18,20,35H,6-7,9-11,14,16-17,33H2,1-2H3/t18-,20+/s2
KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
Article
US Patent
n/an/a<10n/an/an/an/an/an/a



Incyte Corporation

US Patent


Assay Description
Pim-1 and Pim-3 kinase assays-20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...


US Patent US9802918 (2017)


Article DOI: 10.1021/jm031057+
BindingDB Entry DOI: 10.7270/Q2F47R9T
More data for this
Ligand-Target Pair