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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-3' and Ligand = 'BDBM352139'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase pim-3


(Homo sapiens (Human))
BDBM352139
PNG
(4-[(1R,3S,5S)-3-Amino-5-methylcyclohexyl]-N-{[6-(2...)
Show SMILES C[C@@H]1C[C@H](N)C[C@@H](C1)c1ccncc1NCc1ccc(F)c(n1)-c1c(F)cc(cc1F)N1CCOCC1
Show InChI InChI=1S/C28H32F3N5O/c1-17-10-18(12-19(32)11-17)22-4-5-33-16-26(22)34-15-20-2-3-23(29)28(35-20)27-24(30)13-21(14-25(27)31)36-6-8-37-9-7-36/h2-5,13-14,16-19,34H,6-12,15,32H2,1H3/t17-,18+,19-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
Article
US Patent
n/an/a<10n/an/an/an/an/an/a



Incyte Corporation

US Patent


Assay Description
Pim-1 and Pim-3 kinase assays-20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...


US Patent US9802918 (2017)


Article DOI: 10.1021/jm031057+
BindingDB Entry DOI: 10.7270/Q2F47R9T
More data for this
Ligand-Target Pair