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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-3' and Ligand = 'BDBM352158'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase pim-3


(Homo sapiens (Human))
BDBM352158
PNG
(4-[(3R,4R)-3-Amino-4-fluoropiperidin-1-yl]-N-{[6-(...)
Show SMILES N[C@@H]1CN(CC[C@H]1F)c1ccncc1NCc1ccc(F)c(n1)-c1c(F)cccc1F
Show InChI InChI=1/C22H21F4N5/c23-14-7-9-31(12-18(14)27)20-6-8-28-11-19(20)29-10-13-4-5-17(26)22(30-13)21-15(24)2-1-3-16(21)25/h1-6,8,11,14,18,29H,7,9-10,12,27H2/t14-,18-/s2
KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
Article
US Patent
n/an/a<10n/an/an/an/an/an/a



Incyte Corporation

US Patent


Assay Description
Pim-1 and Pim-3 kinase assays-20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...


US Patent US9802918 (2017)


Article DOI: 10.1021/jm031057+
BindingDB Entry DOI: 10.7270/Q2F47R9T
More data for this
Ligand-Target Pair