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Found 8 Enz. Inhib. hit(s) with Target = 'Serine racemase' and Ligand = 'BDBM14673'
TargetSerine racemase(Mus musculus)
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM14673(Fragment 3 | Malonic Acid | propanedioic acid)
Affinity DataKi:  2.70E+4nMAssay Description:Inhibition of mouse serine racemase by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine racemase(Homo sapiens (Human))
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM14673(Fragment 3 | Malonic Acid | propanedioic acid)
Affinity DataKi:  3.30E+4nMAssay Description:Binding affinity to serine recemase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine racemase(Homo sapiens (Human))
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM14673(Fragment 3 | Malonic Acid | propanedioic acid)
Affinity DataKi:  5.90E+4nMAssay Description:Inhibition of human recombinant serine racemase expressed in Escherichia coli Rosetta 2 (DE3) cells using L-serine as substrate by horseradish peroxi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine racemase(Homo sapiens (Human))
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM14673(Fragment 3 | Malonic Acid | propanedioic acid)
Affinity DataKi:  6.60E+4nMAssay Description:Inhibition of hexa-His-tagged purified human recombinant serine racemase expressed in Escherichia coli BL21 Codonplus (DE3)-RIL cells assessed as red...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine racemase(Mus musculus)
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM14673(Fragment 3 | Malonic Acid | propanedioic acid)
Affinity DataKi:  7.10E+4nMAssay Description:Inhibition of mouse recombinant serine racemase transfected in bacterial expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine racemase(Homo sapiens (Human))
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM14673(Fragment 3 | Malonic Acid | propanedioic acid)
Affinity DataIC50:  2.49E+4nMAssay Description:Inhibition of human recombinant N-terminal His-tagged serine racemase expressed in Escherichia coli BL21(DE3) using L-serine as substrate after 10 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine racemase(Mus musculus)
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM14673(Fragment 3 | Malonic Acid | propanedioic acid)
Affinity DataIC50:  6.70E+4nMAssay Description:Inhibition of mouse serine racemase using L-serine substrate by reversed-phase HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine racemase(Homo sapiens (Human))
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM14673(Fragment 3 | Malonic Acid | propanedioic acid)
Affinity DataIC50:  1.31E+6nMAssay Description:Inhibition of full length human recombinant serine recemase C2DC6D mutant expressed in Escherichia coli BL21 (DE3) assessed as D-serine production af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed