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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serotonin (5-HT) receptor' and Ligand = 'BDBM328395'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM328395
PNG
(6-chloro-3-(difluoromethyl)-1-((3-(4-ethylpiperazi...)
Show SMILES CCN1CCN(CC1)c1cc(ccc1OC)S(=O)(=O)n1cc(C(F)F)c2ccc(Cl)cc12
Show InChI InChI=1S/C22H24ClF2N3O3S/c1-3-26-8-10-27(11-9-26)20-13-16(5-7-21(20)31-2)32(29,30)28-14-18(22(24)25)17-6-4-15(23)12-19(17)28/h4-7,12-14,22H,3,8-11H2,1-2H3
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PC cid
PC sid
UniChem
US Patent
n/an/a 0.130n/an/an/an/an/an/a



SUNSHINE LAKE PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the compound of this invention to human 5-HT6 receptor expressed in CHO cell was evaluated by radioligand binding assay as fo...


US Patent US9663498 (2017)

More data for this
Ligand-Target Pair