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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serotonin (5-HT) receptor' and Ligand = 'BDBM50056376'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50056376
PNG
(3-Amino-2-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]...)
Show SMILES COc1ccccc1N1CCN(CCCSc2nc3ccccc3c(=O)n2N)CC1
Show InChI InChI=1S/C22H27N5O2S/c1-29-20-10-5-4-9-19(20)26-14-12-25(13-15-26)11-6-16-30-22-24-18-8-3-2-7-17(18)21(28)27(22)23/h2-5,7-10H,6,11-16,23H2,1H3
KEGG

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 0.5n/an/an/an/an/an/a



Università di Catania

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against radioligand [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat hippocampal membrane.


J Med Chem 40: 574-85 (1997)


Article DOI: 10.1021/jm950866t
BindingDB Entry DOI: 10.7270/Q2K64H6C
More data for this
Ligand-Target Pair