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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Serotonin 2 (5-HT2) receptor' and Ligand = 'BDBM50227787'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)
BDBM50227787
PNG
(CHEMBL1743933)
Show SMILES Cl.COc1cccc(CCc2ccccc2OCCCCN(C)C)c1
Show InChI InChI=1S/C21H29NO2.ClH/c1-22(2)15-6-7-16-24-21-12-5-4-10-19(21)14-13-18-9-8-11-20(17-18)23-3;/h4-5,8-12,17H,6-7,13-16H2,1-3H3;1H
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
13n/an/an/an/an/an/an/an/a



Mitsubishi Kasei Corporation

Curated by ChEMBL


Assay Description
Inhibition of 5-hydroxytryptamine 2 induced vasoconstriction of rat caudal artery.


J Med Chem 33: 1818-23 (1990)


Article DOI: 10.1021/jm00168a043
BindingDB Entry DOI: 10.7270/Q2FB5559
More data for this
Ligand-Target Pair
Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)
BDBM50227787
PNG
(CHEMBL1743933)
Show SMILES Cl.COc1cccc(CCc2ccccc2OCCCCN(C)C)c1
Show InChI InChI=1S/C21H29NO2.ClH/c1-22(2)15-6-7-16-24-21-12-5-4-10-19(21)14-13-18-9-8-11-20(17-18)23-3;/h4-5,8-12,17H,6-7,13-16H2,1-3H3;1H
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 62n/an/an/an/an/an/a



Mitsubishi Kasei Corporation

Curated by ChEMBL


Assay Description
Antagonistic activity against 5-hydroxytryptamine 2 receptor on rat frontal cortex membrane.


J Med Chem 33: 1818-23 (1990)


Article DOI: 10.1021/jm00168a043
BindingDB Entry DOI: 10.7270/Q2FB5559
More data for this
Ligand-Target Pair