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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Serotonin 2 (5-HT2) receptor' and Ligand = 'BDBM50227974'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)
BDBM50227974
PNG
(CHEMBL298554)
Show SMILES CN(C)CCCOc1ccc(Cl)cc1CCc1ccccc1
Show InChI InChI=1S/C19H24ClNO/c1-21(2)13-6-14-22-19-12-11-18(20)15-17(19)10-9-16-7-4-3-5-8-16/h3-5,7-8,11-12,15H,6,9-10,13-14H2,1-2H3
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
26n/an/an/an/an/an/an/an/a



Mitsubishi Kasei Corporation

Curated by ChEMBL


Assay Description
Inhibition of 5-hydroxytryptamine 2 induced vasoconstriction of rat caudal artery.


J Med Chem 33: 1818-23 (1990)


Article DOI: 10.1021/jm00168a043
BindingDB Entry DOI: 10.7270/Q2FB5559
More data for this
Ligand-Target Pair
Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)
BDBM50227974
PNG
(CHEMBL298554)
Show SMILES CN(C)CCCOc1ccc(Cl)cc1CCc1ccccc1
Show InChI InChI=1S/C19H24ClNO/c1-21(2)13-6-14-22-19-12-11-18(20)15-17(19)10-9-16-7-4-3-5-8-16/h3-5,7-8,11-12,15H,6,9-10,13-14H2,1-2H3
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 881n/an/an/an/an/an/a



Mitsubishi Kasei Corporation

Curated by ChEMBL


Assay Description
Antagonistic activity against 5-hydroxytryptamine 2 receptor on rat frontal cortex membrane.


J Med Chem 33: 1818-23 (1990)


Article DOI: 10.1021/jm00168a043
BindingDB Entry DOI: 10.7270/Q2FB5559
More data for this
Ligand-Target Pair