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Found 7 Enz. Inhib. hit(s) with Target = 'Sigma non-opioid intracellular receptor 1' and Ligand = 'BDBM50035097'
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Goethe University

Curated by ChEMBL
LigandPNGBDBM50035097(1''-benzyl-3,4-dihydro-2H-spiro[naphthalene-1,4''-...)
Affinity DataKi:  2nMAssay Description:Binding affinity to Guinea pig brain Sigma1 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Goethe University

Curated by ChEMBL
LigandPNGBDBM50035097(1''-benzyl-3,4-dihydro-2H-spiro[naphthalene-1,4''-...)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]-(+)pentazocine from sigma-1 receptor in guinea pig brain membranes after 180 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50035097(1''-benzyl-3,4-dihydro-2H-spiro[naphthalene-1,4''-...)
Affinity DataKi:  2.40nMAssay Description:Binding affinity for sigma receptor of guinea pig whole brain using [3H]-SKF- 100047 radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50035097(1''-benzyl-3,4-dihydro-2H-spiro[naphthalene-1,4''-...)
Affinity DataIC50:  0.260nMAssay Description:Binding affinity towards sigma receptor binding site 1 using [3H](+)-pentazocineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50035097(1''-benzyl-3,4-dihydro-2H-spiro[naphthalene-1,4''-...)
Affinity DataIC50:  0.260nMAssay Description:Compound was evaluated for the binding affinity towards Sigma receptor type 1 using radioligand ([3H]-(+)- Pentazocine) binding assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50035097(1''-benzyl-3,4-dihydro-2H-spiro[naphthalene-1,4''-...)
Affinity DataIC50:  3.80nMAssay Description:In vitro binding affinity against sigma receptor by using [3H]-DTG ([3H]-6) as radioligand in guinea pig cerebellum.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50035097(1''-benzyl-3,4-dihydro-2H-spiro[naphthalene-1,4''-...)
Affinity DataIC50:  12nMAssay Description:Binding affinity towards Sigma receptor type 2 in whole rat brain homogenates except cerebellum using radioligand ([3H]DTG) binding assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed