Found 11 Enz. Inhib. hit(s) with Target = 'Sigma non-opioid intracellular receptor 1' and Ligand = 'BDBM50407300' TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 36.5nMAssay Description:Affinity against Sigma opioid receptor type 2 using [3H]- DTG in rat liver membranesMore data for this Ligand-Target Pair
Affinity DataKi: 37nMAssay Description:Binding affinity at Sigma receptor type 2 on rat liver membranes receptor by [3H]DTG displacement.More data for this Ligand-Target Pair
Affinity DataKi: 37nMAssay Description:Binding affinity was measured on Sigma receptor type 2 using [3H]- DTG as radioligandMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 83.1nMAssay Description:Binding affinity of the compound was measured on Sigma receptor type 1 using [3H]- pentazocine as radioligandMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 83.1nMAssay Description:Binding affinity measured on Sigma receptor type 1 from guinea pig brain membranes using [3H]pentazocine as radioligand.More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 83.1nMAssay Description:Affinity against Sigma opioid receptor type 1 using [3H]-(+)-Pentazocine in guinea pig brain membranesMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 83.4nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 110nMAssay Description:Tested for binding affinity against sigma receptorsMore data for this Ligand-Target Pair
Affinity DataIC50: 8.90nMAssay Description:Compound was evaluated for the binding affinity towards Sigma receptor type 1 using radioligand ([3H]-(+)- Pentazocine) binding assay.More data for this Ligand-Target Pair
Affinity DataIC50: 8.90nMAssay Description:Binding affinity towards sigma receptor binding site 1 using [3H](+)-pentazocineMore data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Binding affinity towards Sigma receptor type 2 in whole rat brain homogenates except cerebellum using radioligand ([3H]DTG) binding assay.More data for this Ligand-Target Pair
