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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Similar to alpha-tubulin isoform 1' and Ligand = 'BDBM50230623'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Similar to alpha-tubulin isoform 1


(Bos taurus)
BDBM50230623
PNG
(CHEMBL10255)
Show SMILES COc1ccc(cc1O)-c1cc(OC)c(OC)c(OC)c1
Show InChI InChI=1S/C16H18O5/c1-18-13-6-5-10(7-12(13)17)11-8-14(19-2)16(21-4)15(9-11)20-3/h5-9,17H,1-4H3
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>4.00E+4n/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Inhibition of glutamate-dependent tubulin polymerization at 30 degrees C(0.25 mM MgCl2)


J Med Chem 35: 1058-67 (1992)


Article DOI: 10.1021/jm00084a011
BindingDB Entry DOI: 10.7270/Q2KS6TSB
More data for this
Ligand-Target Pair
Similar to alpha-tubulin isoform 1


(Bos taurus)
BDBM50230623
PNG
(CHEMBL10255)
Show SMILES COc1ccc(cc1O)-c1cc(OC)c(OC)c(OC)c1
Show InChI InChI=1S/C16H18O5/c1-18-13-6-5-10(7-12(13)17)11-8-14(19-2)16(21-4)15(9-11)20-3/h5-9,17H,1-4H3
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>4.00E+4n/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Concentration required to inhibit the extent of glutamate-dependent tubulin polymerization by 50% at 37 degrees C(1.0 mM MgCl2)


J Med Chem 35: 1058-67 (1992)


Article DOI: 10.1021/jm00084a011
BindingDB Entry DOI: 10.7270/Q2KS6TSB
More data for this
Ligand-Target Pair