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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium/glucose cotransporter 2 (SGLT2)' and Ligand = 'BDBM176460'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium/glucose cotransporter 2 (SGLT2)


(Homo sapiens (Human))
BDBM176460
PNG
(US9688710, 59 1-(1-hydroxy-2-methylpropan-2-yl)-3-...)
Show SMILES CS[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(C)c(Cc2ccc(CCCCCNC(=O)NC(C)(C)CO)cc2)c1
Show InChI InChI=1S/C30H44N2O6S/c1-19-9-14-22(27-25(35)24(34)26(36)28(38-27)39-4)17-23(19)16-21-12-10-20(11-13-21)8-6-5-7-15-31-29(37)32-30(2,3)18-33/h9-14,17,24-28,33-36H,5-8,15-16,18H2,1-4H3,(H2,31,32,37)/t24-,25-,26+,27+,28-/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<10n/an/an/an/a7.3n/a



Lexicon Pharmaceuticals, Inc.

US Patent


Assay Description
Human sodium/glucose co-transporter type 2 (SGLT2; accession number P31639; GI:400337) was cloned into pIRESpuro2 vector for mammalian expression (co...


US Patent US9688710 (2017)


BindingDB Entry DOI: 10.7270/Q2154F7P
More data for this
Ligand-Target Pair