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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium/glucose cotransporter 2 (SGLT2)' and Ligand = 'BDBM50326281'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium/glucose cotransporter 2 (SGLT2)


(Homo sapiens (Human))
BDBM50326281
PNG
(1-(beta-D-Glucopyranosyl)-4-chloro-3-(1-phenyl-1H-...)
Show SMILES OC[C@H]1O[C@@H](Oc2cccc(Cl)c2Cc2cnn(c2)-c2ccccc2)[C@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1/C22H23ClN2O6/c23-16-7-4-8-17(30-22-21(29)20(28)19(27)18(12-26)31-22)15(16)9-13-10-24-25(11-13)14-5-2-1-3-6-14/h1-8,10-11,18-22,26-29H,9,12H2/t18-,19-,20+,21-,22-/s2
UniProtKB/SwissProt

GoogleScholar
CHEMBL
KEGG
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 32n/an/an/an/an/an/a



Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL


Assay Description
Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scint...


J Med Chem 53: 6355-60 (2010)


Article DOI: 10.1021/jm100332n
BindingDB Entry DOI: 10.7270/Q2V69JSS
More data for this
Ligand-Target Pair