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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium/glucose cotransporter 2 (SGLT2)' and Ligand = 'BDBM50326283'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium/glucose cotransporter 2 (SGLT2)


(Homo sapiens (Human))
BDBM50326283
PNG
(1-(beta-D-Glucopyranosyl)-4-methyl-3-(5-(4-fluorop...)
Show SMILES Cc1cccc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c1Cc1ncc(s1)-c1ccc(F)cc1
Show InChI InChI=1/C23H24FNO6S/c1-12-3-2-4-16(30-23-22(29)21(28)20(27)17(11-26)31-23)15(12)9-19-25-10-18(32-19)13-5-7-14(24)8-6-13/h2-8,10,17,20-23,26-29H,9,11H2,1H3/t17-,20-,21+,22-,23-/s2
UniProtKB/SwissProt

GoogleScholar
CHEMBL
KEGG
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 8.10n/an/an/an/an/an/a



Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL


Assay Description
Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scint...


J Med Chem 53: 6355-60 (2010)


Article DOI: 10.1021/jm100332n
BindingDB Entry DOI: 10.7270/Q2V69JSS
More data for this
Ligand-Target Pair