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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium/hydrogen exchanger 1' and Ligand = 'BDBM50191836'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium/hydrogen exchanger 1


(Homo sapiens)
BDBM50191836
PNG
(4-(4-(4-methyl-1H-imidazol-5-yl)piperidin-1-yl)-5-...)
Show SMILES Cc1nc[nH]c1C1CCN(CC1)c1ncncc1-c1ccccc1C
Show InChI InChI=1S/C20H23N5/c1-14-5-3-4-6-17(14)18-11-21-12-24-20(18)25-9-7-16(8-10-25)19-15(2)22-13-23-19/h3-6,11-13,16H,7-10H2,1-2H3,(H,22,23)
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Similars

Article
PubMed
n/an/a 250n/an/an/an/an/an/a



Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human NHE1 expressed in Ap1 cell line


Bioorg Med Chem Lett 16: 4796-9 (2006)


Article DOI: 10.1016/j.bmcl.2006.06.077
BindingDB Entry DOI: 10.7270/Q2DN44P1
More data for this
Ligand-Target Pair