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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium Channel Complex' and Ligand = 'BDBM70967'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium Channel Complex


(Homo sapiens (Human))
BDBM70967
PNG
(US9546164, 122 | US9694002, 122)
Show SMILES CC1(COc2cc(F)c(cc2C2CC2)C(=O)NS(C)(=O)=O)CCN(Cc2cc(Cl)ccc2C(F)(F)F)CC1
Show InChI InChI=1S/C26H29ClF4N2O4S/c1-25(7-9-33(10-8-25)14-17-11-18(27)5-6-21(17)26(29,30)31)15-37-23-13-22(28)20(12-19(23)16-3-4-16)24(34)32-38(2,35)36/h5-6,11-13,16H,3-4,7-10,14-15H2,1-2H3,(H,32,34)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 2.40n/an/an/an/a7.425



GENENTECH, INC.; XENON PHARMACEUTICALS INC.

US Patent


Assay Description
Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...


US Patent US9694002 (2017)


BindingDB Entry DOI: 10.7270/Q24B2ZFG
More data for this
Ligand-Target Pair