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Found 2 Enz. Inhib. hit(s) with Target = 'Sodium channel protein type 10 subunit alpha' and Ligand = 'BDBM181223'
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM181223(US9139529, 66 | US9783501, Compound 66)
Affinity DataIC50:  2nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM181223(US9139529, 66 | US9783501, Compound 66)
Affinity DataIC50:  2nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In DepthDetails US Patent