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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Sodium channel protein type 9 subunit alpha' and Ligand = 'BDBM145263'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM145263
PNG
(US8952169, 114 | US8952169, 42)
Show SMILES CS(=O)(=O)NC(=O)c1cc(Cl)c(OCC2CCCCCC2)cc1F
Show InChI InChI=1S/C16H21ClFNO4S/c1-24(21,22)19-16(20)12-8-13(17)15(9-14(12)18)23-10-11-6-4-2-3-5-7-11/h8-9,11H,2-7,10H2,1H3,(H,19,20)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 44n/an/an/an/a7.425



Xenon Pharmaceuticals Inc.; Genentech, Inc.

US Patent


Assay Description
Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) was tritiated. Three tritiums were incorporated in plac...


US Patent US8952169 (2015)


BindingDB Entry DOI: 10.7270/Q2M04445
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM145263
PNG
(US8952169, 114 | US8952169, 42)
Show SMILES CS(=O)(=O)NC(=O)c1cc(Cl)c(OCC2CCCCCC2)cc1F
Show InChI InChI=1S/C16H21ClFNO4S/c1-24(21,22)19-16(20)12-8-13(17)15(9-14(12)18)23-10-11-6-4-2-3-5-7-11/h8-9,11H,2-7,10H2,1H3,(H,19,20)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 44n/an/an/an/a7.425



Xenon Pharmaceuticals Inc.; Genentech, Inc.

US Patent


Assay Description
Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) was tritiated. Three tritiums were incorporated in plac...


US Patent US8952169 (2015)


BindingDB Entry DOI: 10.7270/Q2M04445
More data for this
Ligand-Target Pair