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Found 2 Enz. Inhib. hit(s) with Target = 'Sodium channel protein type 9 subunit alpha' and Ligand = 'BDBM170177'
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM170177(US9079902, 8)
Affinity DataIC50:  120nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells assessed as inhibition of sodium current at holding potential of -125 mV measured for 3 to 5 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM170177(US9079902, 8)
Affinity DataIC50:  147nMAssay Description:293 cells stably transfected with either Nav 1.7 or with Nav 1.5 were recorded in population patch-clamp mode with the IonWorks® Quattro automated el...More data for this Ligand-Target Pair
In DepthDetails US Patent