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Found 2 Enz. Inhib. hit(s) with Target = 'Sodium channel protein type 9 subunit alpha' and Ligand = 'BDBM311146'
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM311146((S)-2-(4-((1-methyl-1H-indazol- 4-yl)oxy)phenyl)-6...)
Affinity DataIC50:  2.24E+3nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM311146((S)-2-(4-((1-methyl-1H-indazol- 4-yl)oxy)phenyl)-6...)
Affinity DataIC50:  2.24E+3nMAssay Description:The assay buffer was formulated by removing 120 mL from a 1 L bottle of fresh, sterile dH2O (Mediatech, Herndon, Va.) and adding 100 mL of 10×HBSS th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent