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Found 4 Enz. Inhib. hit(s) with Target = 'Sodium channel protein type 9 subunit alpha' and Ligand = 'BDBM50393026'
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393026(CHEMBL2152691 | US9656959, Example 72)
Affinity DataKi:  143nMAssay Description:Blockade of Nav1.7 by electrophysiological patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393026(CHEMBL2152691 | US9656959, Example 72)
Affinity DataKi:  143nMAssay Description:In the alternative, the voltage clamp protocol to examine hNav1.7 currents was as follows. First, the standard current-voltage relationship was teste...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393026(CHEMBL2152691 | US9656959, Example 72)
Affinity DataIC50:  74nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393026(CHEMBL2152691 | US9656959, Example 72)
Affinity DataIC50:  74nMAssay Description:Blockade of Nav1.7 by FLIPR TETRA sodium dye assay in presence of KCl saltMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed