Found 33 Enz. Inhib. hit(s) with Target = 'Sodium-dependent dopamine transporter' and Ligand = 'BDBM30130' 
Affinity DataKi: 11nMAssay Description:Tested in vitro for serotonin(5-HT) neuronal uptake inhibitionMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of New Orleans
Curated by ChEMBL
University Of New Orleans
Curated by ChEMBL
Affinity DataKi: 784nMAssay Description:Displacement of [3H]WIN 35428 from dopamine transporter in Sprague-Dawley rat brain after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of New Orleans
Curated by ChEMBL
University Of New Orleans
Curated by ChEMBL
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of New Orleans
Curated by ChEMBL
University Of New Orleans
Curated by ChEMBL
Affinity DataKi: 1.09E+3nMAssay Description:Inhibition of DAT in rat striatum assessed as [3H]dopamine accumulationMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 1.90E+3nMAssay Description:Binding inhibition towards human dopamine transporterMore data for this Ligand-Target Pair
Affinity DataKi: >2.00E+3nMAssay Description:Tested in vitro for serotonin(5-HT) neuronal uptake inhibitionMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of New Orleans
Curated by ChEMBL
University Of New Orleans
Curated by ChEMBL
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of New Orleans
Curated by ChEMBL
University Of New Orleans
Curated by ChEMBL
Affinity DataKi: >2.50E+3nMAssay Description:Inhibition of [3H]-DA uptake at Dopamine transporter into rat nerve endings (synaptosomes)More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of New Orleans
Curated by ChEMBL
University Of New Orleans
Curated by ChEMBL
Affinity DataKi: >2.50E+3nMAssay Description:Inhibition of [3H]DA uptake by dopamine transporter of rat striata synaptosomesMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of New Orleans
Curated by ChEMBL
University Of New Orleans
Curated by ChEMBL
Affinity DataKi: 3.05E+3nMAssay Description:Inhibition of [3H]- DA reuptake into rat striatal synaptosomesMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of New Orleans
Curated by ChEMBL
University Of New Orleans
Curated by ChEMBL
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of New Orleans
Curated by ChEMBL
University Of New Orleans
Curated by ChEMBL
Affinity DataKi: 4.58E+3nMAssay Description:Ability to inhibit high affinity reuptake of [3H]DA from dopamine transporter into nerve endings synaptosomesMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of New Orleans
Curated by ChEMBL
University Of New Orleans
Curated by ChEMBL
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of New Orleans
Curated by ChEMBL
University Of New Orleans
Curated by ChEMBL
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 6.00E+3nMAssay Description:Inhibition constant against dopamine transporterMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 6.67E+3nMAssay Description:Displacement of [125I]RTI55 from human recombinant DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 6.67E+3nM ΔG°: -29.2kJ/mole EC50: 1.95E+4nMpH: 7.4 T: 2°CAssay Description:Binding affinity of each compound was measured by assessing the potency of inhibition of binding of radiolabeled RTI-55. Membranes were preincubated ...More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of New Orleans
Curated by ChEMBL
University Of New Orleans
Curated by ChEMBL
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of [3H]DA reuptake at DA transporter in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of DA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of dopamine uptake at human DAT expressed in HEK cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of New Orleans
Curated by ChEMBL
University Of New Orleans
Curated by ChEMBL
Affinity DataIC50: 6.00E+3nMAssay Description:Displacement of [125I]RTI55 from DAT in Sprague-dawley rat striatum by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of dopamine uptake at human DAT in human HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMpH: 7.4Assay Description:DA transporter binding assay for evaluating binding of the compound to the dopamine transporter was carried out using human recombinant dopamine tran...More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.84E+4nMAssay Description:Inhibition of DA reuptake at human DAT expressed in HEK293 cells after 15 mins by fluorescence neurotransmitter transporter assayMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.84E+4nMAssay Description:Inhibition of human DAT expressed in HEK293 cells at incubated for 15 mins by neurotransmitter reuptake assayMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.84E+4nMAssay Description:Inhibition of human DAT expressed in HEK293 cells assessed as inhibition of dopamine reuptake after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.95E+4nMAssay Description:Inhibition of [3H]DA from human recombinant DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKd: 3.60E+3nMAssay Description:Equilibrium dissociation constant (KD) for Competitive binding between [3H]WIN-35428 and the compound at human transporter-hDATMore data for this Ligand-Target Pair
