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Found 10 Enz. Inhib. hit(s) with Target = 'Sodium-dependent dopamine transporter' and Ligand = 'BDBM50006781'
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50006781((2S,3S)-methyl 8-methyl-3-p-tolyl-8-aza-bicyclo[3....)
Affinity DataKi:  5nMAssay Description:Binding affinity to dopamine transporter (DAT) using [3H]WIN-35428 as a radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50006781((2S,3S)-methyl 8-methyl-3-p-tolyl-8-aza-bicyclo[3....)
Affinity DataKi:  5.80nMAssay Description:Binding affinity of compound on dopamine transporters of rat striated membranes using [3H]- mazindol.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50006781((2S,3S)-methyl 8-methyl-3-p-tolyl-8-aza-bicyclo[3....)
Affinity DataKi:  6.90nMAssay Description:Binding affinity for [3H]DA (Dopamine transporter) uptake by striated synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50006781((2S,3S)-methyl 8-methyl-3-p-tolyl-8-aza-bicyclo[3....)
Affinity DataIC50:  1.70nMAssay Description:Binding affinity against Dopamine transporter using [3H]WIN-35 428 in rat striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50006781((2S,3S)-methyl 8-methyl-3-p-tolyl-8-aza-bicyclo[3....)
Affinity DataIC50:  1.70nMAssay Description:Displacement of [3H]WIN-35428 from DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50006781((2S,3S)-methyl 8-methyl-3-p-tolyl-8-aza-bicyclo[3....)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of [3H]WIN-35428l binding to Dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50006781((2S,3S)-methyl 8-methyl-3-p-tolyl-8-aza-bicyclo[3....)
Affinity DataIC50:  7.5nMAssay Description:Inhibitory activity determined for [3H]DA (Dopamine transporter) uptake by striated synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50006781((2S,3S)-methyl 8-methyl-3-p-tolyl-8-aza-bicyclo[3....)
Affinity DataIC50:  11nMAssay Description:Inhibitory activity on dopamine transporter of rat striated membranes using [3H]- mazindol.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50006781((2S,3S)-methyl 8-methyl-3-p-tolyl-8-aza-bicyclo[3....)
Affinity DataIC50:  23.4nMAssay Description:Displacement of [3H]WIN-35428 from DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50006781((2S,3S)-methyl 8-methyl-3-p-tolyl-8-aza-bicyclo[3....)
Affinity DataIC50:  23.4nMAssay Description:Displacement of [3H]WIN-35428 from DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed