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Found 3 Enz. Inhib. hit(s) with Target = 'Sodium-dependent serotonin transporter' and Ligand = 'BDBM50102010'
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50102010(3-[4-(3,4-Dihydro-1H-isoquinolin-2-yl)-cyclohexyl]...)
Affinity DataKi:  1.20nMAssay Description:In vitro for its binding affinity for serotonin transporter RB5-HT-T in rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Institut FüR InterdisziplinäRe Isotopenforschung

Curated by ChEMBL
LigandPNGBDBM50102010(3-[4-(3,4-Dihydro-1H-isoquinolin-2-yl)-cyclohexyl]...)
Affinity DataKi:  4.51nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Institut FüR InterdisziplinäRe Isotopenforschung

Curated by ChEMBL
LigandPNGBDBM50102010(3-[4-(3,4-Dihydro-1H-isoquinolin-2-yl)-cyclohexyl]...)
Affinity DataKi:  189nMAssay Description:Displacement of [3H]paroxetine from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed