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Found 4 Enz. Inhib. hit(s) with Target = 'Sodium-dependent serotonin transporter' and Ligand = 'BDBM50132686'
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50132686(CHEMBL326466 | Dimethyl-((2S,3S)-3-naphthalen-2-yl...)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]-citalopram from Serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50132686(CHEMBL326466 | Dimethyl-((2S,3S)-3-naphthalen-2-yl...)
Affinity DataIC50:  9nMAssay Description:In vitro ability of compound to inhibit 5-HT re-uptake of radiolabelled [3H]-tritium trasmitter into synaptosomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50132686(CHEMBL326466 | Dimethyl-((2S,3S)-3-naphthalen-2-yl...)
Affinity DataIC50:  9nMAssay Description:Inhibition of SERT (unknown origin) assessed as reduction of [3H]5-HT re-uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50132686(CHEMBL326466 | Dimethyl-((2S,3S)-3-naphthalen-2-yl...)
Affinity DataIC50:  9nMAssay Description:Inhibitory concentration against serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed