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Found 4 Enz. Inhib. hit(s) with Target = 'Sodium-dependent serotonin transporter' and Ligand = 'BDBM50191615'
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50191615((3R)-(-)-3-{Cyclobutyl[3-(5-fluoro-1H-indol-3-yl)p...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]paroxetine from serotonin transporter in Sprague-Dawley rat frontal cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50191615((3R)-(-)-3-{Cyclobutyl[3-(5-fluoro-1H-indol-3-yl)p...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]paroxetine from 5-HT transporter in Sprague-Dawley rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50191615((3R)-(-)-3-{Cyclobutyl[3-(5-fluoro-1H-indol-3-yl)p...)
Affinity DataIC50:  18.7nMAssay Description:Inhibition of 5-HT transporter-mediated [3H]5HT uptake in human Jar cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50191615((3R)-(-)-3-{Cyclobutyl[3-(5-fluoro-1H-indol-3-yl)p...)
Affinity DataIC50:  18.7nMAssay Description:Inhibition of [3H]5-HT uptake at human 5-HT transporter expressed in Jar cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed